Month: May 2020

What’s New in Malaria Epidemiology?

What are the strategies to eliminate malaria? Public Domain Images Malaria is an infectious disease transmitted through the bite of Anopheles mosquitoes. The single-celled parasites of the Plasmodium genus are the cause for this disease, and are further classified into over a hundred species of which five (Plasmodium falciparum, P. vivax, P. malariae, P. ovale,  and P. knowlesi) primarily infect humans resulting in flu-like symptoms (including fever, headache, and nausea). The average incubation period is 2 weeks but can be many months for some species. P. falciparum causes the most severe and potentially fatal form of malaria if prompt...

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Most severe austerity measures in Europe are associated with worse child health outcomes

European governments responses to the 2008 Great Recession The Great Recession of 2008 was characterized by an economic and financial crisis with a decline in gross domestic product (GDP), high levels of unemployment, and a great impact on European countries and worldwide. Austerity measures taken by governments as a response to this crisis were characterized by reducing social spending and increasing taxation, although they were neither homogeneous nor similarly implemented at European level; some countries protected public sector programs and systems while others instituted large budget cuts in education, healthcare, and other public services. There was general agreement that...

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A promising new malaria vaccine candidate

Malaria infected red blood cell (coloured blue) Source: NIAID/NHI The best means to attack the parasite Malaria parasites enter the body with the saliva that female mosquitoes inject during blood feeding. This stage of the parasite, the sporozoite, rapidly makes its way to the liver where it multiplies inside the liver cells to form merozoites. When these merozoites enter the blood stream and invade red blood cells (RBC) the parasites transform into a feeding stage, the trophozoite. Schematic focused on the erythrocytic stage of the malaria parasite. Source: Enomoto et al 2012, PLoS One. Here, most of the parasites...

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The WHO International Clinical Trials Registry Platform: Providing global clinical trial information to all

© Martial Trezzini / KEYSTONE / picture alliance The Registry Network Understanding the research landscape to identify gaps and address specific needs is essential to ensure that limited research funds are targeted most appropriately, and, in the case of health research, to ultimately benefit health worldwide. Established in 2006, the ICTRP is now housed within the Research for Health department of the WHO Science Division. The platform’s mission is to ensure that a complete view of clinical trials is accessible to all those involved in healthcare decision-making. This will improve research transparency and will ultimately strengthen the validity and...

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How is the WHO trial registry network responding to the COVID-19 pandemic?

© Pawel / Outside of China and neighboring locations, studies on COVID-19 started to be added to clinical trial registries in March 2020. Registries have responded by updating policies and procedures to make information on clinical research rapidly accessible to all. Facilitating searching Following the recognition in February/March 2020 that COVID-19 had spread to locations outside China, the WHO network of primary trial registries has been implementing ways of prioritising COVID-19 research and making it easy to find. Since 19th March 2020, the WHO has required that all registries ensure that its preferred term ‘COVID-19’ appears in the...

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