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Finding an Effective Spanish-Language Assessment Tool for Alzheimer’s Disease
Amyloid beta peptides aggregate into fibrils, which then form dense plaques on nerve cells, which are involved in Alzheimer’s disease. Juan Gärtner / stock.adobe.com Alzheimer’s disease is the term given to a progressive condition where proteins build up in the brain over time, forming abnormal structures. These accumulations increasingly damage cells, and lead to the…
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It’s not just a headache! A patient’s perspective on the advances in migraine treatment over the last 25 years
© kieferpix / Getty Images / iStock You’ve had migraine for the last 25 years, what myths about migraine would you like to dispel? “It’s just a headache”; “all migraines are the same”; “they only last a few minutes/hours”; I often hear comments like these. It is not just a headache and the symptoms vary…
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How do sex hormones influence migraine?
Of the one billion people worldwide that suffer from migraines, the vast majority of them are women. Roughly one in four women will experience migraine in their lives, compared to one in 16 men, making migraine one of the leading serious health problems affecting women. © iagodina / Getty Images / iStock Migraine affects women…
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The New Era Of Disease Modifying Migraine Drugs (DMMDs)
Migraine treatment has almost always relied on repurposing medication developed to treat other conditions. However, the emergence of novel preventative drugs, bespoke for migraine is in reach. © Andrzej Tokarski / stock.adobe.com Migraine is the most common debilitating disease in the world, affecting about 14% of the global population, or one billion people worldwide. It…
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European Headache Federation guidelines for the use of monoclonal antibodies in migraine prevention: from evidence to recommendations
© ustas / stock.adobe.com Raffaele Ornello What is the aim of the guideline and what is the European Headache Federation (EHF) hoping to achieve for patients and physicians? Several trials have tested the efficacy and safety of the new anti-CGRP monoclonal antibodies. The aim of the guideline was to summarize the available evidence and provide…
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Is aerobic exercise an effective treatment strategy for patients with migraine?
© FS-Stock / stock.adobe.com Migraine is a highly prevalent disorder. Patients with migraine often use acute medication to reduce an acute migraine attack or prophylactic medication to prevent migraine attacks from occurring. However, not all patients tolerate these drugs equally and some might request non-pharmacological alternatives. Non-pharmacological prophylactic treatments like self-management strategies, manual therapy and…
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How animal models are helping us understand migraine and cluster headache symptoms
Primary headache disorders such as migraine are very common and their mechanisms are not entirely understood. Aside from being painful, headache disorders are also disabling. Migraine has recently been ranked as the second highest cause of years lost due to disability worldwide. Cluster headache is another disabling primary headache and extremely painful form of trigeminal…
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Transcranial direct current stimulation and motor rehabilitation: a timely opportunity to boost recovery of brain lesions
The human, social and economic impact of brain disorders (BDs) is huge. BDs impair quality of life, cause a substantial loss of productivity and resource utilization with high economic costs in every country of the world. The majority of the socioeconomic burden of BDs is caused by the years of active life lost because of…
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Virtual reality for stroke: is gaming effective for recovery?
©SpecsLab2019 Every two seconds someone suffers a stroke. Around 55 to 75% of stroke survivors will display impairments and will need long-term care and rehabilitation. These staggering numbers highlight a pressing need to resolve the stroke crisis which accounts for a total estimated annual cost of €45 billion. Current rehabilitation treatments for stroke either do…